44/22 on a 26 is 52" gear. That's what a lot of SS MTB guys run, and it's basically the "standard" 20inch BMX ratio, expressed in gear inches (44/16 BITD, 25/9 today...a lot of different combos with the same inches in-between). So, yeah, I look at that as pretty low for street use, but I live in SJersey, where streets're flat and despite being fat and old, I ride daily. My street singlespeed cruiser runs a 44/18 (64"), and when I was a bit younger, I pushed a 48/16 on skinny 700x25c tires w/ a fixed gear--- came in at 79". But that bike weighed 18lbs; my Worksman tops 50lb.
Ramblin' again.
In summary: depends on the rider, the terrain, and the bike. But what goes up most come down....you'll be spinning fast w/ 44/22 going downhill.